Histone H3, available at Basic Pharma
Histone H3 is a key nucleosomal protein for epigenetics research. Order high-quality Histone H3 from Basic Pharma to ensure consistency and reliability in your laboratory workflows. Contact our specialists to request a quote or place an order.
International supply of recombinant Histone H3
Basic Pharma delivers recombinant Histone H3 to customers worldwide, offering a high-purity, animal-free alternative that supports cutting-edge research in oncology, immunology and other advanced fields.
Benefits of recombinant Histone H3 from Escherichia coli
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Animal-free and free from viral contamination
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>95% purity verified by SDS-PAGE and HPLC
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Lyophilized powder for long-term stability and storage
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Manufactured in an EU-GMP facility
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Batch-to-batch consistency
A pure, single Histone H3 variant
Traditionally, histones are isolated from animal tissues such as calf thymus, resulting in heterogeneous mixtures of variants. Basic Pharma has developed a robust Escherichia coli expression platform enabling the production of a single Histone H3 variant with a purity of >95%.
Through optimized upstream processes (gene integration and fermentation) and advanced downstream purification (filtration and chromatography), we deliver recombinant Histone H3 that is animal-free, highly consistent and suitable for sensitive research workflows.
Are you interested in our recombinant Histone H3? Please contact us via biotech@basicpharma.nl or +31 (0)88 255 40 10!
Histone H3 flyer
Download our Histone H3 leaflet
Applications
Recombinant Histone H3 is widely used in epigenetics and chromatin research. Recent studies indicate its relevance in research related to sepsis progression, oncology and genetic disorders. Compared to animal-derived histones, recombinant Histone H3 offers a safer, more defined and reproducible alternative for advanced research applications.
Recombinant Protein Production Services
This Histone H3 has been developed and manufactured through a collaboration between Basic Pharma (NL) and Maastricht University (NL), combining the expertise of both a research institute and an industrial company in the field of protein engineering.
We are pleased to extend this service to new clients, providing customized solutions for the development and manufacturing of novel recombinant proteins and biopharmaceuticals.
We offer fully customized solutions for clients looking to develop novel recombinant proteins or improve the scalability and quality of their existing products. Our services cover:
- Custom gene design and strain development
- Upstream and downstream process optimization
- Small- to large-scale manufacturing
- Full analytical support and documentation
Specifications
| Product name | Recombinant Histone H3 |
| Source | Bacteria – Escherichia coli |
| Appearance | White grains/powder Lyophilized from Buffer (25 mM HEPES + 140 mM NaCl) |
| Packaging sizes | 100 µg | 1 mg |
| Purity | > 95% pure based on SDS PAGE |
| Safety | No risk of animal derived contaminations (e.g. viral particles/pathogens) |
| Storage conditions and Stability | Lyophilized (at least 6 months at -80 °C) Reconstituted (typical 1 week @ 4 °C) |
| Disclaimer: This product is for R&D and manufacturing purposes only. Not for direct therapeutic use. | |
| Number of Amino Acids | AA 1 – 136 (148 total, incl. Tag etc) |
| Tag | 6x Histidine Tag with Thrombin Cleavage Site |
| Molecular weight | 16760 Da |
| Extinction Coefficient | 4470 M-1 cm-1 |
| Sequence | HHHHHHLVPR GSMARTKQTA RKSTGGKAPR KQLATKAARK SAPSTGGVKK PHRYRPGTVA LREIRRYQKS TELLIRKLPF QRLVREIAQD FKTDLRFQSA AIGALQEASE AYLVGLFEDT NLCAIHAKRV TIMPKDIQLA RRIRGERA |
Interested in our recombinant Histone H3?
We are happy to discuss how this product can support your research or manufacturing needs.
Please contact us via biotech@basicpharma.nl or +31 (0)88 255 40 10 or fill in the form below: