Recombinant Human Serum Albumin (rHSA) from Yeast Expression
Human Serum Albumin (HSA) is the most abundant protein in human plasma, essential for maintaining osmotic pressure and transporting key molecules. Through recombinant protein production, we offer a safer, animal-free alternative: recombinant HSA (rHSA), produced in genetically engineered Hansenula polymorpha yeast.
Global availability of rHSA
Basic Pharma supplies recombinant human serum albumin to customers worldwide, combining high product quality with dependable international logistics to support research and biomanufacturing across multiple regions.
High-Purity, Animal-Free rHSA
Our rHSA is produced through a yeast-based recombinant protein expression platform. The HSA gene is inserted into the genome of Hansenula polymorpha, enabling the yeast’s endogenous protein machinery to produce tag-free rHSA.
The developed production process includes optimized upstream process development (gene integration, fermentation) and downstream purification (filtration, chromatography), resulting in high-purity rHSA (>95%).
Are you interested in our rHSA? Please contact us for more information.
Benefits of rHSA from Hansenula polymorpha
-
Animal-free and free from viral contamination
-
95% purity verified by SDS-PAGE and HPLC
-
Lyophilized powder for long-term stability and storage
-
Ready-to-use: reconstitution requires no dialysis
-
Manufactured in an EU-GMP facility
-
Batch-to-batch consistency
Our Tag-free HSA is chemically and functionally identical to the plasma-derived HSA.
Applications
Our recombinant human serum albumin (rHSA) is highly versatile and widely used in research and biomanufacturing. As an animal-free, high-purity alternative to plasma-derived albumin, it supports both ethical sourcing and regulatory compliance in advanced biotech workflows.
- Supplementation of cell culture media
- Protein stabilizer in ELISA and Western Blot assays
- Excipient in formulation and drug delivery studies
- Use in vaccine development and diagnostic platforms
Recombinant Protein Production Services
This rHSA has been developed and manufactured through a collaboration between Basic Pharma (NL) and ARTES Biotechnology (DE), combining the expertise of both companies in the field of protein engineering.
We are pleased to extend this service to new clients, providing customized solutions for the development and manufacturing of novel recombinant proteins and biopharmaceuticals.
We offer fully customized solutions for clients looking to develop novel recombinant proteins or improve the scalability and quality of their existing products. Our services cover:
- Custom gene design and strain development
- Upstream and downstream process optimization
- Small- to large-scale manufacturing
- Full analytical support and documentation
Specifications
| Specifications | |
|---|---|
| Product name | Tag-Free Recombinant Human Serum Albumin (rHSA) |
| Source | Yeast – Hansenula polymorpha |
| Appearance | White grains/powder Lyophilized from sterile filtered water |
| Packaging sizes | Sizes upon request |
| Purity | > 95% pure based on SDS PAGE and HPLC |
| Safety | No risk of animal derived contaminations (e.g. viral particles/pathogens) |
| Storage conditions and Stability | Lyophilized (typical 2 weeks @ RT | up to 12 months when frozen) Reconstituted (typical 1 week @ RT | up to 6 months when frozen) |
| Disclaimer: This product is for R&D and manufacturing purposes only. Not for direct therapeutic use. | |
| Number of Amino Acids | AA 25 – 609 (585) |
| Molecular weight | 66.472 Da |
| Extinction Coefficient | 34.445 M-1 cm-1 |
| Sequence | DAHKSEVAHR FKDLGEENFK ALVLIAFAQY LQQCPFEDHV KLVNEVTEFA KTCVADESAE NCDKSLHTLF GDKLCTVATL RETYGEMADC CAKQEPERNE CFLQHKDDNP NLPRLVRPEV DVMCTAFHDN EETFLKKYLY EIARRHPYFY APELLFFAKR YKAAFTECCQ AADKAACLLP KLDELRDEGK ASSAKQRLKC ASLQKFGERA FKAWAVARLS QRFPKAEFAE VSKLVTDLTK VHTECCHGDL LECADDRADL AKYICENQDS ISSKLKECCE KPLLEKSHCI AEVENDEMPA DLPSLAADFV ESKDVCKNYA EAKDVFLGMF LYEYARRHPD YSVVLLLRLA KTYETTLEKC CAAADPHECY AKVFDEFKPL VEEPQNLIKQ NCELFEQLGE YKFQNALLVR YTKKVPQVST PTLVEVSRNL GKVGSKCCKH PEAKRMPCAE DYLSVVLNQL CVLHEKTPVS DRVTKCCTES LVNRRPCFSA LEVDETYVPK EFNAETFTFH ADICTLSEKE RQIKKQTALV ELVKHKPKAT KEQLKAVMDD FAAFVEKCCK ADDKETCFAE EGKKLVAASQ AALGL |
Interested in our products?
We would be happy to discuss how it can support your needs. For first-time orders, we offer an introductory discount - just get in touch to learn more!
Please contact us via biotech@basicpharma.nl or +31 (0)88 255 40 10 or fill in the form below: