Recombinant Histone H3 – Animal-Free, High-Purity Protein
A pure, single Histone variant
Histone H3 is a fundamental component of the nucleosome, the core structural unit of chromatin. It plays a crucial role in DNA packaging, gene regulation, and epigenetic modification.
Basic Pharma’s recombinant Histone H3 is a high-purity, animal-free protein produced in Escherichia coli under strict quality-controlled conditions. The product is ideal for research, diagnostic, and early biopharmaceutical applications that require consistent and contaminant-free protein material.
Are you interested in our recombinant Histone H3? Please contact us via biotech@basicpharma.nl or +31 (0)88 255 40 10!
Benefits of recombinant Histone H3 from Escherichia coli
- >95% purity, verified by SDS-PAGE and HPLC
- Animal-free production, eliminating contamination risks
- Single, homogeneous variant — no isoform mixture
- Batch-to-batch consistency ensuring reproducible results
- Lyophilized format for long-term stability and easy handling
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Delivered with Certificate of Analysis (CoA)
Produced under stringent quality systems in the Netherlands.
Histone H3 flyer
Download our Histone H3 leaflet
Applications
Recombinant Histone H3 is suitable for a wide range of research and development applications, including:
- Epigenetics and chromatin biology
- Post-translational modification studies (methylation, acetylation)
- Cancer and sepsis research
- Antibody validation and assay development
- Reference material for analytical testing
Recent studies link circulating Histone H3 to disease progression in cancer and inflammatory conditions, highlighting its value as a biomarker and research target.
Technical Specifications Histon H3
| Attribute | Details |
|---|---|
| Purity | >95% (SDS-PAGE, HPLC) |
| Expression host | E. coli |
| Format | Lyophilized powder |
| Buffer | 25 mM HEPES + 140 mM NaCl |
| Variant | H3.3 Single homogeneous recombinant variant |
| Animal-derived materials | None |
| Use | For R&D and manufacturing purposes only |
Disclaimer
For research and manufacturing use only. Not for direct therapeutic or diagnostic use in humans.
Development and Collaboration
This recombinant Histone H3 was developed in collaboration with Maastricht University, combining academic expertise with Basic Pharma’s proven know-how in bioprocess development, protein purification, and scale-up.
Our Biotech division supports custom requests, including:
- Alternative expression systems
- Protein engineering and manufacturing
- Custom purification or formulation
Learn more about our custom recombinant protein expression services.
Request Information or Sample
Interested in our recombinant Histone H3?
Contact our Biotech team at biotech@basicpharma.nl or call +31 (0)88 255 40 10.
You can also complete the inquiry form to request a sample or quotation tailored to your research needs.
Interested in our products?
We would be happy to discuss how it can support your needs. For first-time orders, we offer an introductory discount - just get in touch to learn more!
Please contact us via biotech@basicpharma.nl or +31 (0)88 255 40 10 or fill in the form below: